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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLEC1 All Species: 18.18
Human Site: Y246 Identified Species: 57.14
UniProt: Q15149 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15149 NP_000436.2 4684 531791 Y246 N V Q I A L D Y L R H R Q V K
Chimpanzee Pan troglodytes XP_520008 4393 493952 A228 E A M S G E D A E V R A V A E
Rhesus Macaque Macaca mulatta XP_001088212 4683 532114 Y246 N V Q I A L D Y L R H R Q V K
Dog Lupus familis XP_539204 4686 532886 Y251 N V Q I A L D Y L R H R Q V K
Cat Felis silvestris
Mouse Mus musculus Q9QXS1 4691 534197 Y257 N V Q I A L D Y L R H R Q V K
Rat Rattus norvegicus P30427 4687 533521 Y252 N V Q I A L D Y L R H R Q V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001093502 4577 522590 V233 I A E R D L G V T R L L D P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00963 2291 265721
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.7 98.1 92.6 N.A. 93.5 93.5 N.A. N.A. N.A. N.A. 62.1 N.A. 20.5 N.A. N.A. N.A.
Protein Similarity: 100 87.4 98.9 96.1 N.A. 96.6 96.5 N.A. N.A. N.A. N.A. 80.2 N.A. 32.5 N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. N.A. N.A. 13.3 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. N.A. N.A. N.A. 26.6 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 0 0 63 0 0 13 0 0 0 13 0 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 13 0 75 0 0 0 0 0 13 0 0 % D
% Glu: 13 0 13 0 0 13 0 0 13 0 0 0 0 0 25 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 13 0 13 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 63 0 0 0 0 % H
% Ile: 13 0 0 63 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63 % K
% Leu: 0 0 0 0 0 75 0 0 63 0 13 13 0 0 0 % L
% Met: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 63 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % P
% Gln: 0 0 63 0 0 0 0 0 0 0 0 0 63 0 0 % Q
% Arg: 0 0 0 13 0 0 0 0 0 75 13 63 0 0 0 % R
% Ser: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % T
% Val: 0 63 0 0 0 0 0 13 0 13 0 0 13 63 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 63 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _